Scientific Background

Evidence-Driven Excellence: High-Impact Research Shaping the Future of TMJ Science

The Centre's work is grounded in rigorous clinical trials, translational research, and multidisciplinary innovation. Over the past three decades, this research has advanced the global understanding of temporomandibular joint pathology, biomechanics, imaging, and surgical reconstruction, providing a robust evidence base for the standards the Centre teaches.

Key Scientific Highlights

• A recognised body of research in temporomandibular joint surgery and evidence-based management of temporomandibular joint disorders
• China's first multicentre Phase III randomised controlled trial in oral oncology, published in the Journal of Clinical Oncology
• Multicentre longitudinal studies on temporomandibular joint reconstruction, craniofacial deformities, adolescent disc displacement, and growth-related joint disorders
• A clinical cohort of over 10,000 patients, forming one of the world's largest TMJ research databases
• Extensive collaborations across Europe, North America, and Asia, sustaining a high citation impact
• Contributions to international temporomandibular joint guidelines, consensus statements, and best-practice frameworks that shape global clinical standards

The research underpinning the Centre has established international benchmarks in TMJ diagnosis, MRI-based imaging protocols, joint biomechanics and function, digital surgical planning, outcome assessment, and functional recovery — providing a robust evidence foundation for modern TMJ surgical practice worldwide.

Disc displacement

• Influence of local factors on the condylar growth after arthroscopic discopexy
• New arthroscopic disc
• An arthroscopic technique for
• Techniques of Yang’s
• Association between bilateral condylar resorption and reduced volumes of the craniofacial skeleton and masticatory muscles in adult patients
• Yang’s Classification of Juvenile TMJ Anterior Disc Displacement Contributing to Treatment protocols.pdf
• Imaging evaluation of disc position and status after temporomandibular joint arthroscopic disc repositioning and suturing surgery.
• Efficacy of Arthroscopic Diskopexy on Condylar Growth in Temporomandibular Joint Anterior Disk Displacement A Randomized Clinical Trial
• Malocclusion Associated With Temporomandibular Joint Anterior Disc Displacement and Condylar Resorption in Adolescents A Cross-Sectional Study
• Effect of arthroscopic discopexy on condylar growth in adolescents with temporomandibular joint disc displacement without reduction A retrospective self-controlled case series study

Joint replacement

• Clinical application of customized total temporomandibular joint prosthesis by 3D printing a five-year follow-up study
• Introduction of temporomandibular joint and skull base combined reconstruction by autogenous bone graft
• 3D-printed temporomandibular joint-mandible combined prosthesis A prospective study
• Endoscopically assisted fixation of the custom-made total temporomandibular joint prosthesis in TMJ Yang's system through
• Skull Base Erosion Resulting From Primary Tumors of the Temporomandibular Joint and Skull Base Region